The theory of Parkinson's disease development from HPA Axis dysfunction is premised on hypothalamic control of the Fight/Flight/Freeze Response (our instinctive response to danger). This response to perceived danger dramatically increases adrenal output of adrenaline/epinephrine, cortisol, testosterone, nor-adrenaline and aldosterone. Together, these chemicals allow us to utilise increased energy to oppose a threat to our safety (Fight), run away from danger (Flight), or remain motionless to avoid detection (Freeze). While this is a remarkably effective way to maintain safety, and has served humanity well over millennia, continuous production of cortisol in the face of unresolvable stress can create long term damage in metabolic function. The type of damage and ultimate results are, in part, dependant on genetic programming, but also of life choices and environment3.
When we display symptoms of Parkinson's disease, we are already under significant stress from the disease process. Diagnosis increases our stress levels, especially if the diagnosis is presented, as so often, by a professional who gives no hope for improvement or self-help, and no support for personal investigation or activities.
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